It Must Have Been Difficult
Have you ever stopped to think about how Paul must have felt as he was in prison and facing possible execution. Those on whom he should have been able to depend on for help and support had forsaken him.
2 Timothy 1:15-16 KJV
This thou knowest, that all they which are in Asia be turned away from me; of whom are Phygellus and Hermogenes.  The Lord give mercy unto the house of Onesiphorus; for he oft refreshed me, and was not ashamed of my chain:
2 Timothy 4:16-18 KJV
At my first answer no man stood with me, but all men forsook me: I pray God that it may not be laid to their charge.  Notwithstanding the Lord stood with me, and strengthened me; that by me the preaching might be fully known, and that all the Gentiles might hear: and I was delivered out of the mouth of the lion.
 And the Lord shall deliver me from every evil work, and will preserve me unto his heavenly kingdom: to whom be glory for ever and ever. Amen.
But Paul knew that God was with him, stood by him, strengthened him and would preserve him unto his heavenly kingdom.
With that assurance he could face whatever he encountered.
After so many years of work and toil, caring for the lost and the saved, it must have been hard for him to come to the closing days of his service and seem to have to stand alone. He prayed for those who had neglected him and did not want God to hold it to their charge.
Can you find a more noble spirit than that manifested by Paul?
Nonetheless, his heart must have ached in disappointment and sadness to feel all had forsaken him and none stood with him in his final days.